Search Results - subject:"microarray"

Orthology-Based Multilevel Modeling of Differentially Expressed Mouse and Human Gene Pairs

Ogorek, Benjamin; Stefanski, Leonard - In: Statistical Applications in Genetics and Molecular Biology 8 (2009) 1, pp. 2-2

There is great interest in finding human genes expressed through pharmaceutical intervention, thus opening a genomic window into benefit and side-effect profiles of a drug. Human insight gained from FDA-required animal experiments has historically been limited, but in the case of gene expression...

Persistent link: https://www.econbiz.de/10005585054

A Nonlinear Mixed-Effects Model for Estimating Calibration Intervals for Unknown Concentrations in Two-Color Microarray Data with Spike-Ins

Thilakarathne, Pushpike; Verbeke, Geert; Engelen, Kristof; … - In: Statistical Applications in Genetics and Molecular Biology 8 (2009) 1, pp. 5-5

In this study, we propose a calibration method for preprocessing spiked-in microarray experiments based on nonlinear … intervals for two publicly available cDNA microarray experiments (Hilson et al., 2004; Smets et al., 2008). This method can … easily be adapted to preprocess one-color oligonucleotide microarray data with a slight adjustment to the mixed model. …

Persistent link: https://www.econbiz.de/10005585055

Information matrix for a mixture of two Laplace distributions

Choi, Dongseok; Nadarajah, Saralees - In: Statistical Papers 50 (2009) 1, pp. 1-12

Persistent link: https://www.econbiz.de/10005759988

Survival Analysis with High-Dimensional Covariates: An Application in Microarray Studies

Engler, David; Li, Yi - In: Statistical Applications in Genetics and Molecular Biology 8 (2009) 1, pp. 14-14

Use of microarray technology often leads to high-dimensional and low-sample size (HDLSS) data settings. A variety of … of microarray data obtained from a set of patients with diffuse large B-cell lymphoma where time to survival is of …

Persistent link: https://www.econbiz.de/10005246465

Game Theory applied to gene expression analysis.

Moretti, Stefano - Université Paris-Dauphine - 2009

analysis of gene expression data. Nowadays, microarray technology is available for taking “pictures” of gene expressions …

Persistent link: https://www.econbiz.de/10008799435

Hierarchical Bayesian meta-analysis models for cross-platform microarray studies

Conlon, E. M.; Postier, B. L.; Methe, B. A.; Nevin, K. P.; … - In: Journal of Applied Statistics 36 (2009) 10, pp. 1067-1085

findings across multiple-platform studies. A common goal of microarray analysis is to identify genes with differential …-analysis model to pool gene expression studies from different microarray platforms: spotted DNA arrays and short oligonucleotide …

Persistent link: https://www.econbiz.de/10008466709

Optimization of gene-environment networks in the presence of errors and uncertainty with Chebychev approximation

Weber, G.-W.; Taylan, P.; Alparslan-Gök, S.; … - In: TOP: An Official Journal of the Spanish Society of … 16 (2008) 2, pp. 284-318

Persistent link: https://www.econbiz.de/10005371422

S. POMBE GENE REGULATORY NETWORK INFERENCE USING THE FUZZY LOGIC NETWORK

CAO, YINGJUN; YU, LINGCHU; TOKUTA, ALADE; WANG, PAUL P. - In: New Mathematics and Natural Computation (NMNC) 04 (2008) 01, pp. 61-76

In this paper, we first study the stability and convergence property of fuzzy logic networks (FLN). A random approach is adopted to simulate the convergence speed and steady-state properties based on four fuzzy logical functions. The simulation results show that MV logical function causes the...

Persistent link: https://www.econbiz.de/10004965147

Data Distribution of Short Oligonucleotide Expression Arrays and Its Application to the Construction of a Generalized Intellectual Framework

Konishi, Tomokazu - In: Statistical Applications in Genetics and Molecular Biology 7 (2008) 1, pp. 25-25

Information obtained by microarray studies frequently cause discrepancies between projects, laboratories and/or even …

Persistent link: https://www.econbiz.de/10005585064

Correcting the Estimated Level of Differential Expression for Gene Selection Bias: Application to a Microarray Study

Bickel, David - In: Statistical Applications in Genetics and Molecular Biology 7 (2008) 1, pp. 10-10

the level of differential gene expression. In a microarray data set, the bias correction reduces estimates of the …

Persistent link: https://www.econbiz.de/10005585070