The quadratic assignment problem (QAP) is a challenging combinatorial problem. The problem is NP-hard and in addition, it is considered practically intractable to solve large QAP instances, to proven optimality, within reasonable time limits. In this paper we present an attractive mixed integer...

The share of renewable liquid fuels (ethanol, fatty acid methyl ester, biogas, and renewable electricity) in the total transportation fuel in Sweden, has increased by the end of 2009 to such level that e.g. domestic bioethanol production is unable to satisfy current ethanol fuel demand. Regional...

In this paper, we consider a variant of the Location-Routing Problem (LRP), namely the LRP with simultaneous pickup and delivery (LRPSPD). The LRPSPD seeks to minimize total cost by simultaneously locating the depots and designing the vehicle routes that satisfy pickup and delivery demand of...

This paper presents the effect of implementing interruptible loads (ILs) from the demand side for reserve allocation in an electricity supply system. A unit commitment (UC) objective function is used to incorporate the energy/reserve providers and to schedule energy and reserves simultaneously....

We develop a finite-horizon discrete-time constrained Markov decision process (MDP) to model diagnostic decisions after mammography where we maximize the total expected quality-adjusted life years (QALYs) of a patient under resource constraints. We use clinical data to estimate the parameters of...

We consider a model for determining optimal opportunistic maintenance schedules w.r.t. a maximum replacement interval. This problem generalizes that of Dickman et al. (J Oper Res Soc India 28:165–175, 1991 ) and is a natural starting point for modelling replacement schedules of more complex...