Nonlinear state space models with mixed-effect (NLMESSM) are proposed to model HIV clinical longitudinal data. With NLMESSM, filtering algorithms are proposed to estimate the individual/population states. Maximum likelihood via iterated filtering and variance components model are proposed to...

Particle filters are numerical methods for approximating the solution of the filtering problem which use systems of weighted particles that (typically) evolve according to the law of the signal process. These methods involve a corrective/resampling procedure which eliminates the particles that...

. The Adaptive Multiple Importance Sampling algorithm is aimed at an optimal recycling of past simulations in an iterated importance sampling (IS) scheme. The difference with earlier adaptive IS implementations like Population Monte Carlo is that the importance weights of all simulated values,...

In this review we explore issues of the sensitivity of Bayes estimates to the prior and form of the likelihood. With respect to the prior, we argue that non-Bayesian analyses also incorporate prior information, illustrate that the Bayes posterior mean and the frequentist maximum likelihood...