the intrinsic mean on the shape space. We compare the performance of our proposed procedure to the usual GDA using a real …

emergence of a complex network in shape space is outlined, the edges of which are characterised by both direction and weight …

Shape space was proposed by Perelson and Oster 20 years ago as a conceptual formalism in which to represent antibody … abstract "shape space" where coordinates of points in this space represent generalized physico-chemical properties associated …. Distances in shape space between points representing antibodies and (the shape complement of) antigens are assumed to be related …

approximations of D. G. Kendall's non-Euclidean shape space is given, and the equivalence of several methods based on orthogonal …

threshold affinity for an antigen lie in a region of shape space that we call a {\it ball of stimulation}. In a cross … of balls of stimulation in different shape spaces, and show that the parameters of shape space, such as its … dimensionality, have a large impact on the number of B cells in the intersection. We present a method for deriving shape space …