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clinical trials 1 continuous covariates 1 fractional polynomials 1 mfpi 1 mfpi plot 1 stepp plot 1 stepp tail 1 stepp window 1 subpopulation treatment-effect pattern plot 1 treatment-covariate interaction 1
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Royston, Patrick 1 Sauerbrei, Willi 1
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Two techniques for investigating interactions between treatment and continuous covariates in clinical trials
Royston, Patrick; Sauerbrei, Willi - In: Stata Journal 9 (2009) 2, pp. 230-251
There is increasing interest in the medical world in the possibility of tailoring treatment to the individual patient. Statistically, the relevant task is to identify interactions between covariates and treatments, such that the patient’s value of a given covariate influences how strongly (or...
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