Pertsemlidis, Alexander; Zelinka, Jan; Fondon, John; … - In: Statistical Applications in Genetics and Molecular Biology 4 (2007) 1, pp. 35-35
We describe a method for the generation of knowledge-based potentials and apply it to the observed torsional angles of known protein structures. The potential is derived using Bayesian reasoning, and is useful as a prior for further such reasoning in the presence of additional data. The...