In assessing the mechanism of treatment efficacy in randomized clinical trials, investigators often perform mediation analyses by analyzing if the significant intent-to-treat treatment effect on outcome occurs through or around a third intermediate or mediating variable: indirect and direct...

Abstract In randomized controlled trials, the evaluation of an overall treatment effect is often followed by effect modification or subgroup analyses, where the possibility of a different magnitude or direction of effect for varying values of a covariate is explored. While studies of effect...

We further the theoretical understanding of group faultlines (hypothetical lines that split a group into subgroups based on two or more demographic attributes; Lau & Murnighan, 1998) in demographically diverse organizations by also conceptualizing the distance of difference between the two...

We introduce the concept of faultline distance that reflects the extent to which subgroups formed by faultlines diverge as a result of accumulated differences across them (e.g., two members of age 20 are closer in age to two members of an opposing faultline of age 25 than of two members of age...

Abstract We address several questions relating to the use of standard regression and Structural Nested Mean Model (SNMM) approach (e. g., Ten Have et al. 2007) to analyze post-randomization effect modifiers of the intent-to-treat effect of a randomized intervention on a subsequent outcome,...