Instrumental variables can be used to make inferences about causal effects in the presence of unmeasured confounding. For a model in which the instrument, intermediate/treatment, and outcome variables are all binary, Balke and Pearl (1997, Journal of the American Statistical Association 92:...

We describe a method to estimate associations between random effects from multilevel models. We provide two new postestimation commands, reffadjustsim and reffadjust4nlcom, which are distributed as the reffadjust package. These commands produce the estimates and their associated confidence...

Funnel plots are currently advocated to investigate the presence of publication bias (and other possible sources of bias) in meta-analysis. A previously described augmentation to the funnel plot—to aid its interpretation in assessing publication biases—is the addition of statistical contours...

There is an increasing need to establish whether health-care interventions are cost effective as well as clinically effective. It is becoming increasingly common for cost studies to be incorporated into clinical trials, either on all patients or more usually on a subset of patients. Establishing...

Decision analytical models are widely used in economic evaluation of health care interventions with the objective of generating valuable information to assist health policy decision-makers to allocate scarce health care resources efficiently. The whole decision modelling process can be...

In this article, we describe a suite of commands that enable the user to estimate the probability that the conclusions of a meta-analysis will change with the inclusion of a new study, as described previously by Sutton et al. (2007, Statistics in Medicine 26: 2479–2500). Using the metasim...