When the mortality among a cancer patient group returns to the same level as in the general population, that is, when the patients no longer experi- ence excess mortality, the patients still alive are considered “statistically cured”. Cure models can be used to estimate the cure proportion...

When estimating patient survival using data collected by populationbased cancer registries, it is common to estimate net survival in a relative-survival framework. Net survival can be estimated using the relative-survival ratio, which is the ratio of the observed survival of the patients (where...

Cancer registries are often interested in estimating net survival (NS), the probability of survival if the cancer under study is the only possible cause of death. Pohar Perme, Stare, and Esteve (2012, Biometrics 68: 113–120) proposed a new estimator of NS based on inverse probability...

I will give a brief overview of modern statistical methods for estimating treatment effects that have recently become popular in social and biomedical sciences. These methods are based on the potential outcome framework developed by Donald Rubin. The specific methods discussed include regression...

It is usual in time-to-event data to have more than one event of interest, for example, time to death from different causes. Competing risks models can be applied in these situations where events are considered mutually exclusive absorbing states. That is, we have some initial state—for...

There is an increasing need to establish whether health-care interventions are cost effective as well as clinically effective. It is becoming increasingly common for cost studies to be incorporated into clinical trials, either on all patients or more usually on a subset of patients. Establishing...

This article focuses on the modelling and prediction of costs due to disease accrued over time, to inform the planning of future services and budgets. It is well documented that the modelling of cost data is often problematic due to the distribution of such data; for example, strongly right...

Age–period–cohort models provide a useful method for modeling incidence and mortality rates. It is well known that age–period–cohort models suffer from an identifiability problem due to the exact relationship between the variables (cohort = period − age). In 2007, Carstensen published...

Competing risks are present when the patients within a dataset could experience one or more of several exclusive events and the occurrence of any one of these could impede the event of interest. One of the measures of interest for analyses of this type is the cumulative incidence function....