The arrival of personalized medicine in the clinic means that treatment decisions will increasingly rely on test results. The challenge of limited health care resources means that the dissemination of these technologies will be dependent on their value in relation to their cost; i.e. their cost...

Background: Trastuzumab has significantly improved survival outcomes for women with HER2 positive early breast cancer. Trastuzumab was established as a costeffective adjuvant treatment in 2006. We present an updated cost-effectiveness analysis from the UK perspective which explores assumptions...

The challenge of implementing high cost innovative technologies in health care systems operating under significant budgetary pressure has seen a radical shift in the health technology reimbursement landscape. New reimbursement strategies attempt to reduce the risk of making the wrong decision;...

Background: Levels of measles in England and Wales are at their highest for 18 years and strategies targeting the different groups of parents who don’t vaccinate their children continue to be needed. Decision aids for childhood immunisation decisions appear to be effective in achieving vaccine...

Health care systems are increasingly under pressure to provide funding for innovative technologies. These technologies tend to be characterized by their potential to make valued contributions to patient health in areas of relative unmet need, high acquisition costs and great uncertainty in the...

Background: Diagnostic tests are often evaluated according to how the results will change clinical management. Patients may value information even if the management does not change. Objective: To investigate the willingness of adults with inherited retinal disease to undergo and pay for...

Lay involvement in public health programmes occurs through formalised lay health worker (LHW) and other volunteer roles. Whether such participation should be supported, or indeed rewarded, by payment is a critical question. With reference to policy in England, UK, this paper argues how framing...

Purpose – The creation of the Patient Advice and Liaison Service (PALS) was part of a range of measures to make the NHS more patient‐centred. The purpose of this paper is to present a critical analysis of PALS through examining the impact on major stakeholder groups....

The arrival of personalized medicine in the clinic means that treatment decisions will increasingly rely on test results. The challenge of limited healthcare resources means that the dissemination of these technologies will be dependent on their value in relation to their cost, i.e., their cost...