Given rising healthcare costs and a growing population of patients with chronic kidney disease (CKD), there is an urgent need to identify health interventions that provide good value for money. For this review, the English-language literature was searched for studies of interventions in CKD...

One-third to two-thirds of men are not adherent to bisphosphonates. Non-adherence is associated with increased fracture risk. Estimates of direct and indirect osteoporosis-related fracture costs are also substantial in men, and may even be more costly than in women. More robust data would better...

Current guidelines recommend the use of warfarin in all patients with atrial fibrillation (AF) and/or an artificial heart valve who are at high risk of thromboembolism. While anticoagulation with warfarin greatly reduces this risk, a careful system of monitoring and management is necessary to...

These results suggest that use of amlodipine may reduce costs of care among CAD patients with normal blood pressure. </AbstractSection> Copyright Adis Data Information BV 2008

Objectives To analyse 2-year hospitalization and cost data collected during a prospective, double-blind, randomized, controlled trial comparing amlodipine, enalapril and placebo in normotensive patients with coronary artery disease (CAD). Methods All patients who were enrolled in the CAMELOT...

Background: Although various prescription drugs may be equally effective in promoting sleep, some may lead to substantial impairment in psychomotor functioning and an increased risk of motor vehicle accidents. Objective: To develop a general model to evaluate the potential effects of sleep...

Zusammenfassung Der Klimawandel stellt den Wintertourismus in Mittelgebirgen und Mittelgebirgslagen vor große Herausforderungen. Dieser Bericht stellt die Ergebnisse einer Untersuchung zur Wichtigkeit der Schneesicherheit für die Reiseentscheidung von Wintertouristen in diesen Regionen dar. Es...

The paper investigates how far the state-of-the-art technology of the internet can contribute to the creation of a barrier-free city. The paper begins with a discussion of the general possibilities and potential of the internet for disabled people. This discussion is followed by a presentation...