A new procedure is proposed to balance typeI andII errors in significance testing for differential expression of individual genes. Suppose that a collection, , of k lists of selected genes is available, each of them approximating by their content the true set of differentially expressed genes....

Canine hip dysplasia (CHD) is characterized by hip laxity and subluxation that can lead to hip osteoarthritis. Studies have shown the involvement of multiple genetic regions in the expression of CHD. Although we have associated some variants in the region of fibrillin 2 with CHD in a subset of...

The aims of this study were to undertake principal component analysis (PCA) of hip dysplasia (HD) and to examine the power of the principal components (PCs) in genome-wide association studies. A cohort of 278 dogs for PCA and that of 369 dogs for genotyping were used. The distraction index (DI),...

Purpose: The study aims to examine a discrepant industrial case that demonstrates how to achieve economies of scale with additive manufacturing (AM), thereby expanding the scope of AM beyond high-variety, customised production contexts. Design/methodology/approach: Abductive reasoning is...