We consider how to represent sigmoid-type regression relationships in a practical and parsimonious way. A pure sigmoid relationship has an asymptote at both ends of the range of a continuous covariate. Curves with a single asymptote are also important in practice. Many smoothers, such as...

Environmental risks may comprise the most important policy-related application of the economics of risk and uncertainty. Many biases in risk assessment and regulation, such as the conservatism bias in risk assessment and the stringent regulation of synthetic chemicals, reflect a form of...

Methods for capturing images in three dimensions are now widely available, with stereo-photogrammetry and laser scanning being two common approaches. In anatomical studies, a number of landmarks are usually identified manually from each of these images and these form the basis of subsequent...

The penalized spline method has been widely used for estimating univariate smooth functions based on noisy data. This paper studies its extension to the two-dimensional case. To accommodate the need of handling data distributed on irregular regions, we consider bivariate splines defined on...

We aim at modeling the survival time of intensive care patients suffering from severe sepsis. The nature of the problem requires a flexible model that allows to extend the classical Cox-model via the inclusion of time-varying and nonparametric effects. These structured survival models are very...

We consider the estimation problem of conditional quantile when multi-dimensional covariates are involved. To overcome the “curse of dimensionality” yet retain model flexibility, we propose two partially linear models for conditional quantiles: partially linear single-index models (QPLSIM)...