This Test Guideline describes an assay that assesses early life-stage effects and potential adverse consequences of …. In the test, fish are exposed, from newly fertilized egg until the completion of sexual differentiation at about 60 days … post hatch, to at least three concentrations of the test substance dissolved in water. In each treatment level and control …

This Test Guideline is designed to assess the toxicity of substances to freshwater aquatic plants of the genus Lemna … monocultures in, at least, five concentrations of the test substance over a period of seven days. The objective of the test is to …. The limit test corresponds to one dose level of 100 mg/L. This study includes measurement of pH, light intensity …

This test measures chromosome events in spermatogonial germ cells and is, therefore, expected to be predictive of … test substance (liquid or solid) by an appropriate route of exposure, usually by gavage or by intraperitoneal injection … analysable males. Test substances are preferably administered once or twice but they may also be administered as a split dose to …

This Test Guideline lists methods for determining the density of liquids and solids, giving only a very succinct …

The bacterial reverse mutation test uses amino-acid requiring at least five strains of Salmonella typhimurium and … test is that it detects mutations which revert mutations present in the test strains and restore the functional capability … of the bacteria to synthesize an essential amino acid. Suspensions of bacterial cells are exposed to the test substance …

test substance (liquid, solid, vapour or gas, …) indicates that the substance has affected germinal tissue of the test … anomalies), but gene mutations and toxic effects cannot be excluded. This Test Guideline recommends rats or mice as the test … species. Generally, male animals are exposed to the test substance and mated to untreated virgin females. The most widely used …

This Test Guideline describes methods to measure the viscosity of liquids. The methods listed are appropriate in …

This Test Guideline describes a method which is an adaptation of the Soap and Detergent Association semi …-continuous activated sludge (SCAS) procedure for assessing the primary biodegradation of alkyl benzene sulphonate. The test does not … an aeration (SCAS) unit. The test compound (non-volatile, water soluble, organic, non-inhibitoring to bacteria at the …

This Test Guideline lists methods for determining the density of liquids and solids, giving only a succinct description …

This test measures structural chromosomal aberrations (both chromosome- and chromatid-type) in dividing spermatogonial … purpose of the in vivo mammalian spermatogonial chromosomal aberration test is to identify those chemicals that cause … structural chromosomal aberrations in mammalian spermatogonial cells (1) (2) (3). In addition, this test is relevant to assessing …