This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that encode for all the key enzymes for...

This annual report, covering events in 1994, is a concise factual compendium of cross-country trade and trade-related developments. It chronicles intense activity in the world trading system: the historic signing of the Final Act of the Uruguay Round; preparations for the entry into force of the...

This report describes the complex and changing interrelationship between trade, domestic investment and foreign direct investment (FDI) and provides examples of good practices in trade policymaking that create a healthy investment climate in developing countries. A two-by-two taxonomy is used to...

This report examines the impact of policy interdependence on how governments regulate. It has two purposes. The first is to understand better the dynamics of thc emerging multi-governmental regulatory system, and the relationships, institutions, and processes that comprise its working parts. The...