Background: The Investigating Choice Experiments for the Preferences of Older People (ICEPOP) programme developed a capability-based measure of general quality of life (QOL): the ICEPOP CAPability (ICECAP-O) instrument. ICECAP-O was originally intended for use in the economic evaluation of...

Background: Fibromyalgia (FM) is a chronic disorder characterized by persistent and widespread pain, often accompanied with fatigue, sleep disturbance and other symptoms. FM affects a population mostly of a productive age and is thus associated with significant lost productivity and disability,...

Background: The REDUCE trial examined whether chemoprevention with the dual 5-alpha reductase inhibitor, dutasteride, reduced risk of prostate cancer (PCa) detection on biopsy. Objective: We examined the cost effectiveness of dutasteride compared with placebo in preventing PCa in men at...

Background: Generic drugs have been advocated to decrease the proportion of healthcare costs devoted to drugs, but are still underused. Objective: To assess citizens' preferences for brand name drugs (BNDs) compared with generic drugs for treating acute and chronic conditions. Methods: A...

Background: Consideration of public preferences is desirable when making decisions on the subsidy of pharmaceuticals. Little is known about the preferences of the public for pharmaceutical funding decisions, and no study has directly compared the preferences of members of a pharmaceutical...

In Germany, the Institute for Quality and Efficiency in Health Care (IQWiG) makes recommendations for ceiling prices of drugs based on an evaluation of the relationship between costs and effectiveness. To set ceiling prices, IQWiG uses the following decision rule: the incremental...

Background: Patients with gallbladder and common bile duct stones are generally treated by pre-operative endoscopic sphincterotomy (ES) followed by laparoscopic cholecystectomy (POES). Recently, a meta-analysis has shown that intra-operative ES during laparoscopic cholecystectomy (IOES) results...

Background: Evidence about how people value health gains for different age groups is controversial and incomplete, despite the significance of this issue for priority setting in health policy. Objective: The aim of this study was to collect and analyse nationally representative data in the US...

Background:Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and potentially fatal disease. Little is known about the economic burden associated with CTEPH patients in the US. Abstract: Objectives:Objectives: The objective of this study was to estimate excess direct...