Purpose Frequent itemset mining (FIM) is a basic topic in data mining. Most FIM methods build itemset database containing all possible itemsets, and use predefined thresholds to determine whether an itemset is frequent. However, the algorithm has some deficiencies. It is more fit for discrete...

Purpose The traditional drug development process is costly, time consuming and risky. Using computational methods to discover drug repositioning opportunities is a promising and efficient strategy in the era of big data. The explosive growth of large-scale genomic, phenotypic data and all kinds...

Purpose Neuroscience data are spread across a variety of sources, typically provisioned through ad-hoc and non-standard approaches and formats and often have no connection to the related data sources. These make it difficult for researchers to understand, integrate and reuse brain-related data....