We consider contracting issues in the care of patients with chronic conditions within the principal-agent framework. The government, acting as a principal, contracts with several health care providers in an effort to maximise population health minus the cost. We consider the decision of whether...

We explore the procurement of influenza vaccines by a government whose objective is to minimize the expected social costs (including vaccine, vaccine administration, and influenza treatment costs) when a for-profit vaccine supplier has production yield uncertainty, private information about its...

Type 2 Diabetes Mellitus (T2DM), the epidemic of the 21st century, accounts for 4.6 million deaths globally and for 11% of the global health expenditure. Several different public health, primary preventive, and secondary interventions promise better health outcomes and cost savings. This paper...

We propose and analyze the first model for clinical trial design that integrates each of three important trends intending to improve the effectiveness of clinical trials that inform health-technology adoption decisions: adaptive design, which dynamically adjusts the sample size and allocation of...

Intensive care units are important departments in hospitals that are complicated in that they have both urgent and elective patients with a variety of specialty needs. Their design involves important operations strategy decisions, such as whether there are several specialized units for certain...

Introduction: The current COVID-19 pandemic leads to a massive influx of patients to the ICU. Epidemic models focus on the demand for care capacity. Here, we present a model for the number of COVID-19 and non-COVID-19 patients that can be served for a given ICU capacity. The results may give...

Health systems are placing increasing emphasis on improving the design and operation of clinical trials, with the aim of making the health technology adoption process more value-based. We present a model of a value-based two-armed clinical trial in which both the recruitment rate and trial...

Search models have traditionally been used to describe situations such as the development of new technology, job search, and the search for profitable investment opportunities. We address the problem faced by a firm that must conduct a search and therefore contemplates outsourcing that process....

We model two agents who can benefit from a mutual deal or partnership, yet are also searching for outside alternatives. This generic situation is observed in various settings (e.g., the job market for experts) and involves several decisions. The proposer decides not only on the timing, deadline,...

Probabilistic forecasts are necessary for robust decisions in the face of uncertainty. The M5 Uncertainty competition required participating teams to forecast nine quantiles for unit sales of various products at various aggregation levels and for different time horizons. This paper evaluates the...