We briefly review and discuss design issues for population growth and decline models. We then use a flexible growth and decline model as an illustrative example and apply optimal design theory to find optimal sampling times for estimating model parameters, specific parameters and interesting...

The desirability function is widely used in the engineering field to tackle the problem of optimizing multiple responses simultaneously. This approach does not account for the variability in the predicted responses and minimizing this variability to have narrower prediction intervals is...