It is known that in many missing data models, for example, survival data models, some parameters are root-n estimable while the others are not. When they are, their limiting distributions are often Gaussian and easy to use. When they are not, their limiting distributions, if exists, are often...

A class of optimal adaptive multi-arm clinical trial designs is proposed based on an extended generalized Polya urn (GPU) model. The design is applicable to both the qualitative and quantitative responses and achieves, asymptotically, some pre-specified optimality criterion. Such criterion is...