The exon tiling array offers a high throughput technology to search for aberrant splicing in biomedical research, but few methods of analysis for splicing detection have been tested both statistically and empirically. Noisy measurements on nonresponsive probe selection regions and outlying...

The reduced-rank regression is an effective method in predicting multiple response variables from the same set of predictor variables. It reduces the number of model parameters and takes advantage of interrelations between the response variables and hence improves predictive accuracy. We propose...