The exon tiling array offers a high throughput technology to search for aberrant splicing in biomedical research, but few methods of analysis for splicing detection have been tested both statistically and empirically. Noisy measurements on nonresponsive probe selection regions and outlying...

Estimation of conditional quantiles at very high or low tails is of interest in numerous applications. Quantile regression provides a convenient and natural way of quantifying the impact of covariates at different quantiles of a response distribution. However, high tails are often associated...