Because many medical decisions are based on risk prediction models that are constructed from medical history and results of tests, the evaluation of these prediction models is important. This paper makes five contributions to this evaluation: the relative utility curve which gauges the potential...

We define a surrogate end point as a measure or indicator of a biological process that is obtained sooner, at less cost or less invasively than a true end point of health outcome and is used to make conclusions about the effect of an intervention on the true end point. Prentice presented...