The aim of the paper is to present methodology for the classification of potential psychotropic drugs on the basis of their activity. We first sketch the background of this class of drugs and then zoom in on so-called pharmacoelectroencephalogram studies. These data pose some statistical...

An item response theory model for dealing with omitted responses in a test is proposed. In this model formulation, non-response does not only depend on an examinee's ability and on item difficulty, but additionally also on 'test speededness'. Using a local-influence-based diagnostic approach,...

Many models to analyse incomplete data have been developed that allow the missing data to be missing not at random. Awareness has grown that such models are based on unverifiable assumptions, in the sense that they rest on the (incomplete) data only in part, but that inferences nevertheless...

In many electrophysiological experiments the main objectives include estimation of the firing rate of a single neuron, as well as a comparison of its temporal evolution across different experimental conditions. To accomplish these two goals, we propose a flexible approach based on the logistic...

"Persistent disturbing behaviour" refers to a chronic condition in highly unstable, therapy resistant psychiatric patients. Because these patients are difficult to maintain in their natural living environment and even in hospital wards, purposely designed residential psychiatric facilities need...

The moment method is a well-known astronomical mode identification technique in asteroseismology which uses a time series of the first three moments of a spectral line to estimate the discrete oscillation mode parameters "l" and "m". The method, in contrast with many other mode identification...

On the basis of serological data from prevalence studies of rubella, mumps and hepatitis A, the paper describes a flexible local maximum likelihood method for the estimation of the rate at which susceptible individuals acquire infection at different ages. In contrast with parametric models that...