We determine optimal crossover designs for the estimation of direct treatment effects in a model with mixed and self carryover effects. The model also assumes that the errors within each experimental unit are correlated following a stationary first-order autoregressive process. The paper...

We focus on estimating daily integrated volatility ( IV ) by realized measures based on intraday returns following a discrete-time stochastic model with a pronounced intraday periodicity (IP). We demonstrate that neglecting the IP-impact on realized estimators may lead to invalid statistical...