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'We Are Not Guinea Pigs' : The Effects of Disclosure of Medical Misconduct on Vaccine Compliance

Archibong, Belinda; Annan, Francis - National Bureau of Economic Research - 2023

In 1996, following an epidemic, Pfizer tested a new drug on 200 children in Muslim Nigeria. 11 children died while others were disabled. We study the effects of the disclosure, in 2000, of the deaths of Muslim children in the Pfizer trials on vaccine compliance among Muslim mothers. Muslim...

Persistent link: https://www.econbiz.de/10014372412

The Diffusion of Science-Driven Drug Discovery : Organizational Change in Pharmaceutical Research

Cockburn, Iain - 1999

question in the context of one particularly interesting practice, the adoption of science driven drug discovery by the modern … pharmaceutical industry. Over the past two decades, the established pharmaceutical industry has slowly shifted towards a more science …. The principal finding is that adoption of a science-oriented research approach was a function of initial conditions, or …

Persistent link: https://www.econbiz.de/10012471425

Pharmaceutical Innovation, Mortality Reduction, and Economic Growth

Lichtenberg, Frank R. - 1998

We perform an econometric investigation of the contribution of pharmaceutical innovation to mortality reduction and growth in lifetime per capita income. In both of the periods studied (1970-80 and 1980-91), there is a highly significant positive relationship across diseases between the increase...

Persistent link: https://www.econbiz.de/10012472240

Investments in Pharmaceuticals Before and After TRIPS

Kyle, Margaret - 2009

We examine the relationship between patent protection for pharmaceuticals and investment in development of new drugs. Patent protection has increased around the world as a consequence of the TRIPS Agreement, which specifies minimum levels of intellectual property protection for members of the...

Persistent link: https://www.econbiz.de/10012463181

The Welfare Effects of Public Drug Insurance

Lakdawalla, Darius - 2007

Rewarding inventors with inefficient monopoly power has long been regarded as the price of encouraging innovation. Public prescription drug insurance escapes that trade-off and achieves an elusive goal: lowering static deadweight loss, while simultaneously encouraging dynamic investments in...

Persistent link: https://www.econbiz.de/10012465145

Did Medicare Induce Pharmaceutical Innovation?

Acemoglu, Daron - 2006

The introduction of Medicare in 1965 was the single largest change in health insurance coverage in U.S. history. Many economists and commentators have conjectured that the introduction of Medicare may have also been an important impetus for the development of new drugs that are now commonly used...

Persistent link: https://www.econbiz.de/10012466722

Opportunities for Improving the Drug Development Process : Results from a Survey of Industry and the FDA

Berndt, Ernst R. - 2005

Based on our survey and discussions, we uncovered several thematic opportunities to improve interactions between the FDA and industry and to reduce clinical development times: 1) develop metrics and goals at the FDA for clinical development times in exchange for PDUFA like fees; 2) establish an...

Persistent link: https://www.econbiz.de/10012467254

Organizational Scope and Investment : Evidence from the Drug Development Strategies and Performance of Biopharmaceutical Firms

Guedj, Ilan - 2004

This paper compares the clinical trial strategies and performance of large, established ("mature") biopharmaceutical firms to those of smaller ("early stage") firms that have not yet successfully developed a drug. We study a sample of 235 cancer drug candidates that entered clinical trials...

Persistent link: https://www.econbiz.de/10012467754

The Impact of Pharmaceutical Innovation on Premature Cancer Mortality in Canada, 2000-2011

Lichtenberg, Frank R. - 2015

The premature cancer mortality rate has been declining in Canada, but there has been considerable variation in the rate of decline across cancer sites. I analyze the effect that pharmaceutical innovation had on premature cancer mortality in Canada during the period 2000-2011, by investigating...

Persistent link: https://www.econbiz.de/10012457428

Improving Regulation for Innovation : Evidence from China's Pharmaceutical Industry

Jia, Ruixue; Ma, Xiao; Yang, Jianan; Zhang, Yiran - National Bureau of Economic Research - 2023

This study investigates how enhanced regulation can promote innovation, focusing on the impacts of a significant regulatory reform in China's pharmaceutical sector implemented in 2015. Inspired by regulatory practices in the U.S., the reform aimed to address application backlogs and reduce...

Persistent link: https://www.econbiz.de/10014447297