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Reconstructing gene regulatory networks from time-series microarray data

Li, S.P.; Tseng, J.J.; Wang, S.C. - In: Physica A: Statistical Mechanics and its Applications 350 (2005) 1, pp. 63-69

A gene regulatory network depicts which genes turn on which and at what moment. Knowledge of such gene networks is key … to an understanding of the biological process. We propose here to use a statistical method for the reconstruction of gene … regulatory networks based on Bayesian networks from microarray data. We describe a nonlinear model for the rate of gene …

Persistent link: https://www.econbiz.de/10010588441

A numerical investigation of adaptation in populations of random boolean networks

Lemke, Ney; Mombach, Jose’e C.M.; Bodmann, Bardo E.J. - In: Physica A: Statistical Mechanics and its Applications 301 (2001) 1, pp. 589-600

We investigate the adaptation of random boolean networks that are a model for regulatory gene networks. The model …

Persistent link: https://www.econbiz.de/10010873785

Relationships between the global structure of genetic networks and mRNA levels measured by cDNA microarrays

Shehadeh, Lina A.; Liebovitch, Larry S.; Jirsa, Viktor K. - In: Physica A: Statistical Mechanics and its Applications 364 (2006) C, pp. 297-314

Previous studies of genetic interactions have focused on measuring and analyzing the level of mRNA expressed by each … gene and then finding statistical correlations between them. Here we focus on assessing the global pattern, not the level … probability density function (PDF) of the mRNA levels produced by each model. Thus, we make a dictionary of the mRNA patterns …

Persistent link: https://www.econbiz.de/10010589497

ncRNA-mediated bistability in the synthesis of hundreds of distinct mRNAs and proteins

Zhdanov, Vladimir P. - In: Physica A: Statistical Mechanics and its Applications 389 (2010) 4, pp. 887-890

The kinetics of gene expression can be bistable due to the feedback between the mRNA and protein formation. In …

Persistent link: https://www.econbiz.de/10010590279

Leader-following coordination of multi-agent systems with coupling time delays

Hu, Jiangping; Hong, Yiguang - In: Physica A: Statistical Mechanics and its Applications 374 (2007) 2, pp. 853-863

In this paper, we consider a leader-following consensus problem of a group of autonomous agents with time-varying coupling delays. Two different cases of coupling topologies are investigated. At first, a necessary and sufficient condition is proved in the case when the interconnection topology...

Persistent link: https://www.econbiz.de/10010588888

Synchronization criteria for a generalized complex delayed dynamical network model

Wang, Lei; Dai, Hua-ping; Sun, You-xian - In: Physica A: Statistical Mechanics and its Applications 383 (2007) 2, pp. 703-713

It has been demonstrated that most complex networks display synchronization phenomena, and this problem has attracted great attention of various fields including science and engineering. In this paper, a generalized complex dynamical network model with time-varying delays was presented....

Persistent link: https://www.econbiz.de/10010589387

Speculative dynamics in a time-delay model of asset prices

Dibeh, Ghassan - In: Physica A: Statistical Mechanics and its Applications 355 (2005) 1, pp. 199-208

In this paper, a time-delay model of speculative asset markets is developed to investigate the effect of time delays on the dynamics of asset prices. The basic model investigates the effect of time delays in the chartists expectations function on the deviation of asset prices from their...

Persistent link: https://www.econbiz.de/10010873690

Consensus in noisy environments with switching topology and time-varying delays

Sun, Yongzheng; Zhao, Donghua; Ruan, Jiong - In: Physica A: Statistical Mechanics and its Applications 389 (2010) 19, pp. 4149-4161

In this paper, the leader-following consensus problem of noise perturbed multi-agent systems with time-varying delays is investigated. We analyze two different cases of coupling topologies: fixed topology and switching topology. Based on the Lyapunov functional and combining with the linear...

Persistent link: https://www.econbiz.de/10010871660

Transitions induced by time delays and cross-correlated sine-Wiener noises in a tumor–immune system interplay

Guo, Wei; Du, Lu-Chun; Mei, Dong-Cheng - In: Physica A: Statistical Mechanics and its Applications 391 (2012) 4, pp. 1270-1280

A model of tumor–immune system interplay with time delays and cross-correlated sine-Wiener noises is investigated by numerical simulations for the stationary probability distribution (SPD) and stationary mean value 〈x〉st of tumor cell population. Results show that (i) the structure of the...

Persistent link: https://www.econbiz.de/10011058243

Time-delay effects on dynamics of a two-actor conflict model

Rojas-Pacheco, A.; Obregón-Quintana, B.; Liebovitch, L.S. - In: Physica A: Statistical Mechanics and its Applications 392 (2013) 3, pp. 458-467

We present a study of time-delay effects on a two-actor conflict model based on nonlinear differential equations. The state of each actor depends on its own state in isolation, its previous state, its inertia to change, the positive or negative feedback and a time delay in the state of the other...

Persistent link: https://www.econbiz.de/10011059494