The Cox proportional hazards model has been used extensively in medicine over the last 40 years. A popular application is to develop a multivariable prediction model, often a prognostic model to predict the clinical outcome of patients with a particular disorder from "baseline" factors measured...

Royston (2014, Stata Journal 14: 738–755) explained how a popular application of the Cox proportional hazards model "is to develop a multivariable prediction model, often a prognostic model to predict the future clinical outcome of patients with a particular disorder from 'baseline' factors...

I provide a new programming tool, cmpute, to manage conveniently the creation of a new variable or the replacement of an existing variable interactively or within a Stata program. Copyright 2013 by StataCorp LP.

We consider how to represent sigmoid-type regression relationships in a practical and parsimonious way. A pure sigmoid relationship has an asymptote at both ends of the range of a continuous covariate. Curves with a single asymptote are also important in practice. Many smoothers, such as...

There is increasing interest in the medical world in the possibility of tailoring treatment to the individual patient. Statistically, the relevant task is to identify interactions between covariates and treatments, such that the patient’s value of a given covariate influences how strongly (or...

Royston and Parmar (2002, Statistics in Medicine 21: 2175 – 2197) developed a class of flexible parametric survival models that were programmed in Stata with the stpm command (Royston, 2001, Stata Journal 1:1-28). In this article, we introduce a new command, stpm2, that extends the...

We present an update of mim, a program for managing multiply im- puted datasets and performing inference (estimating parameters) using Rubin’s rules for combining estimates from imputed datasets. The new features of particular importance are an option for estimating the Monte Carlo error (due...

In this paper, we describe a new Stata command, stlh, which estimates and tests for the significance of the time-varying regression coefficients in Aalen's linear hazards model; see Aalen (1989). We see two potential uses for this command. One may use it as an alternative to a proportional...

A new set of tools is described for performing analyses of an ensemble of datasets that includes multiple copies of the original data with imputations of missing values, as required for the method of multiple imputation. The tools replace those originally developed by the authors. They are based...

Royston (2001)and Royston and Parmar (2002) introduced flexible parametric models for survival analysis, implemented in Stata through the ado-file stpm (Royston 2001). In the present article, stpm is updated to Stata 8.1 and has been shown to work correctly with Stata 8.2. To increase the...