Insufficient confounder adjustment is viewed as a common source of "false discoveries", especially in the epidemiology sector. However, adjustment for "confounders" that are correlated with the exposure, but which do not independently predict the outcome, may cause loss of power to detect the...

The parmest package creates output datasets (or results sets) with one observation for each of a set of estimated parameters, and data on the parameter estimates, standard errors, degrees of freedom, t or z statistics, p-values, confidence limits, and other parameter attributes specified by the...

The cendif module is part of the somersd package, and calculates confidence intervals for the Hodges–Lehmann median difference between values of a variable in two subpopulations. The traditional Lehmann formula, unlike the formula used by cendif, assumes that the two subpopulation...

Splines, including polynomials, are traditionally used to model nonlinear relationships involving continuous predictors. However, when they are included in linear models (or generalized linear models), the estimated parameters for polynomials are not easy for nonmathematicians to understand, and...