We propose the use of metaheuristics for the resource-capacitated multilevel lot-sizing problem with general product structures, setup costs, setup times, and lead times. Initially, we develop a heuristic which moves production in time in order to obtain feasible solutions with good quality....

We consider the two-level network design problem with intermediate facilities. This problem consists of designing a minimum cost network respecting some requirements, usually described in terms of the network topology or in terms of a desired flow of commodities between source and destination...