In this paper the optimal design problem for the estimation of the individual coefficients in a polynomial regression on an arbitrary interval [a, b] (- inf. a b inf) is considered. Recently, Sahm (2000) demonstrated that the optimal design is one of four types depending on the symmetry...

Estimation and experimental design in a non-linear regression model that is used in microbiology are studied. The Monod model is defined implicitly by a differential equation and has numerous applications in microbial growth kinetics, water research, pharmacokinetics and plant physiology. It is...

In this paper D-optimal designs for free knot least squares spline estimation are investigated. In contrast to most of the literature on optimal design for spline regression models it is assumed that the knots of the spline are also estimated from the data, which yields to optimal design...