Background: Identifying differentially expressed genes has been an important and widely used approach to investigate gene functions and molecular mechanisms. A related issue that has drawn much less attention but is equally important is the identification of constantly expressed genes across...

The water footprint is an indicator of freshwater consumption that looks not only at direct water consumption of a consumer or producer, also at the indirect water consumption. The water footprint can be regarded as a comprehensive indicator of freshwater resources appropriation, next to the...

Despite the volume of research conducted on efficient frontiers, in many cases it is still not the easiest thing to compute a mean-variance (MV) efficient frontier even when all constraints are linear. This is particularly true of large-scale problems having dense covariance matrices and hence...