Missing data often arise in practice. The commonly employed approach to handle the missing data is imputation, which is effective when the missing mechanism is known and each subject in the data set misses at random. However, the situation where the imputation is not appropriate often emerged....

Hidden population stratification (PS) is a main concern in the analysis of case-control genetic association studies. All methods to correct for hidden PS have been focused on classical hypothesis testing, and cannot be directly applied to Bayesian analysis. In this paper, to study the impact and...

Non-central chi-squared distribution plays a vital role in commonly used statistical testing procedures. The non-centrality parameter [delta] provides valuable information on the power of the associated test. In this paper, based on one observation X sampled from a chi-squared distribution with...

Modelling of HIV dynamics in AIDS research has greatly improved our understanding of the pathogenesis of HIV-1 infection and guided for the treatment of AIDS patients and evaluation of antiretroviral therapies. Some of the model parameters may have practical meanings with prior knowledge...

type="main" xml:id="sjos12060-abs-0001" <title type="main">ABSTRACT</title>Although efficiency robust tests are preferred for genetic association studies when the genetic model is unknown, their statistical properties have been studied for different study designs separately under special situations. We study some...

This study examined the relationship between loneliness, health, and mortality using a U.S. nationally representative sample of 2101 adults aged 50 years and over from the 2002 to 2008 waves of the Health and Retirement Study. We estimated the effect of loneliness at one point on mortality over...