Quality of life and productivity are two important measures in health outcomes that usually require the use of self-reported surveys for accurate assessment. Measuring health-related quality of life (HRQOL) has been established as an important field in the past century, and many psychometrically...

This paper utilises the Mini-Mental State Examination (MMSE) score of patients with Alzheimer’s disease to establish a relationship between disease progression and quality of life measures, and the author also compares his results to findings from the literature review about Alzheimer’s...

Suppose that one has a clinical dataset with only non-preference-based QOL data, and that one nevertheless would like to perform a cost/QALY analysis. This study reports on some efforts to establish a “mapping” relationship between AQLQ (a non-preference-based QOL instrument for asthma) and...

Background Health Related Quality of Life (HRQoL) measures are becoming more frequently used in clinical trials and health services research, both as primary and secondary endpoints. Investigators are now asking statisticians for advice on how to plan and analyse studies using HRQoL measures,...

This paper reports the results of a study to estimate a statistical health state valuation model for a revised version of the Health Utilities Index Mark 2, using Standard Gamble health state preference data. A sample of 51 health states were valued by a sample of the 198 members of the UK...

Ranking exercises have routinely been used as warm-up exercises within health state valuation surveys. Very little use has been made of the information obtained in this process. Instead, research has focussed upon the analysis of health state valuation data obtained using the visual analogue...

An increasingly important debate has emerged around the extent to which techniques such as the standard gamble, which is used, amongst other things, to value health states, actually serve to construct respondents' preferences rather than simply elicit them. According to standard theory, the...

Preference-based measures of health (PBMH) have been developed primarily for use in economic evaluation. They have two components, a standardized, multidimensional system for classifying health states and a set of preference weights or scores that generate a single index score for each health...

There is increasing interest in using ordinal methods to estimate cardinal values for health states to calculate quality adjusted life years. This paper reports the estimation of models of rank data and discrete choice experiment (DCE) data to derive a preference-based index from a condition...

OBJECTIVES To recruit a panel of members of the public to provide preferences in response to the needs of economic evaluators over the course of a year. METHODS A sample of members of the UK general public was recruited in a stratified random sample from the electoral roll and familiarised with...