Toxicologists have been increasingly using a class of models to describe a continuous response in the last few years. This class consists of nested nonlinear models and is used for estimating various parameters in the models or some meaningful function of the model parameters. Our work here is...

The Michaelis-Menten model has and continues to be one of the most widely used models in many diverse fields. In the biomedical sciences, the model continues to be ubiquitous in biochemistry, enzyme kinetics studies, nutrition science and in the pharmaceutical sciences. Despite its wide ranging...