Showing 1 - 10 of 43,249
This paper investigates the effect of (potential) market size on entry of new drugs and pharmaceutical innovation. Focusing on exogenous changes driven by U.S. demographic trends, we find that a 1 percent increase in the potential market size for a drug category leads to a 4 to 6 percent...
Persistent link: https://www.econbiz.de/10014075002
Our study puts special attention to the fact that R&D cooperations in the pharmaceutical industry are formed at different stages throughout the drug development process. We study if the timing to engage in R&D cooperations in the pharmaceutical industry has different impacts on the technology...
Persistent link: https://www.econbiz.de/10010229875
A generic drug maker that has been sued for infringing a patent on a branded drug will sometimes promise, as part of an agreement settling the litigation, to delay selling its drug until as late as the expiration of the patent term. I adapt the standard optimal patent term model to determine...
Persistent link: https://www.econbiz.de/10014131063
Erstattungsbetragsverhandlungen innovativer Arzneimittel werden als Gefahr für die zukünftige Versorgung der Patienten und für den Forschungs- und … zweckmäßigen Vergleichstherapie gleichwertige Arzneimittel schlechter gestellt werden. Zum anderen können nur noch … Arzneimittel beeinflusst darüber hinaus die Standortentscheidungen pharmazeutischer Unternehmen. …
Persistent link: https://www.econbiz.de/10013468282
The patent laws of many countries have ''research exemption'' provisions that exempt certain research-related uses of proprietary materials from patent infringement. By limiting the rights of existing patent holders, such rules are meant to facilitate follow-on innovation and benefit latecomer...
Persistent link: https://www.econbiz.de/10013241201
According to Gans & Stern (1999), firms engage in R&D spending, in part, in order to improve their bargaining position as buyers in the market for technology. We test this theory empirically with data from the pharmaceutical industry. We develop and estimate a structural model of R&D spending...
Persistent link: https://www.econbiz.de/10014028306
This paper examines the idea that the USA has outshined Europe in the race for new medicines as a result of a flight of business R&D expenditure to the USA. It adopts a methodology that accounts for R&D price inflation, considers the role of both ‘performed' R&D and ‘extra-mural' R&D, and...
Persistent link: https://www.econbiz.de/10013155663
supportive evidence for pharmaceuticals. This study revisits this hypothesis using OECD data for the period 1980-2000. It extends …
Persistent link: https://www.econbiz.de/10013155664
Within the last decades, there have been many technological and regulatory changes in the pharmaceutical industry. Some of these developments facilitate the innovative activities of large firms, while others foster small firms. It is therefore surprising that the implications of these changes in...
Persistent link: https://www.econbiz.de/10011844257
In the last ten years, the pharmaceutical industry has experienced steep, unprecedented price increases. Pharmaceutical companies engage in R&D cooperations to cope with rocketing research and development (R&D) expenses.We study the impact of R&D cooperations on firms' research activities and...
Persistent link: https://www.econbiz.de/10012951300