Quality-adjusted lifetime (QAL) has been playing an important role in clinical trials to evaluate treatments for chronic diseases. Much research has been focused on estimating the mean QAL when the data are subject to right censoring. The estimated mean QAL is often presented with a confidence...

A common problem with laboratory assays is that a measurement of a substance in a test sample becomes relatively imprecise as the concentration decreases. A standard solution is to establish lower limits for reliable measurement. A quantitation limit is a level above which a measurement has...

It has been shown that a smoothing spline estimate is an equivalent kernel estimate. In this paper, we show that both the Nadaraya-Watson and local linear kernel estimators are equivalent penalized estimators.

An effective bandwidth selection method for local linear regression is proposed in Fan and Gijbels [1995, J. Roy. Statist. Soc. Ser. B, 57, 371-394]. The method is based on the idea of the pre-asymptotic substitution and has been tested extensively. This paper investigates the rate of...

We develop analysis of deviance tools for generalized partial linear models based on local polynomial fitting. Assuming a canonical link, we propose expressions for both local and global analysis of deviance, which admit an additivity property that reduces to ANOVA decompositions in the Gaussian...