In existing AS/RS research, storage assignment policies are evaluated based on the probability that item type j will be stored (and subsequently retrieved). This note applies the turnover-based and class-based assignment policies of Hausman et al. (1976) to a stochastic environment by...

Currently available medication for treating many chronic diseases is often effective only for a subgroup of patients, and biomarkers accurately assessing whether an individual belongs to this subgroup do not exist. In such settings, physicians learn about the effectiveness of a drug primarily...

This paper analyzes the costs and benefits of screening women of childbearing age for HIV. The analysis is based on a dynamic compartmental model of the HIV epidemic that incorporates disease transmission and progression over time, behavioral changes, and effects of screening and associated...

We assess the cost-effectiveness of maintenance treatment for heroin addiction, with emphasis on its role in preventing HIV infection. The analysis is based on a dynamic compartmental model of the HIV epidemic among a population of adults, ages 18 to 44. The population is divided into nine...

We present a survey of over 50 representative problems in location research. Our goal is not to review all variants of different location models or to describe solution results, but rather to provide a broad overview of major location problems that have been studied, indicating briefly how they...

We consider the problem of designing a multivehicle automated guided vehicle system (AGVS) to supplement an existing nonautomated material handling system. The AGVS consists of a pool of vehicles that deliver raw components from a central storage area to workcenters throughout the factor floor....

We consider a random yield inventory system, where a company has access to real time information about the actual yield realizations. To contribute to a better understanding of the value of this information, we develop a mathematical model of the inventory system and derive structural...

The European Research Center for Information Systems (ERCIS) was founded on October, 12th 2004. This Working Paper was written with respect to the establishment of ERCIS. Jörg Becker, Managing Director of the ERCIS, writes about fundamental issues of ERCIS. Furthermore all Founding Members...