The only therapy for a patient with end-stage liver disease (ESLD) is liver transplantation, which is performed by using either a cadaveric liver from a deceased donor or a portion of a living-donor's liver. This study addresses the following decision problem for an ESLD patient with an...

Cadaveric liver transplantation is the only viable therapy for end-stage liver disease patients without a living donor. However, this type of transplantation is hindered in the United States by donor scarcity and rapid viability decay. Given these difficulties, the current U.S. liver allocation...

Living donors are a significant and increasing source of livers for transplantation, mainly because of the insufficient supply of cadaveric organs. We consider the problem of optimally timing a living-donor liver transplant to maximize the patient's total reward, such as quality-adjusted life...

End-stage renal disease (ESRD) is the ninth-leading cause of death in the U.S. Transplantation is the most viable renal replacement therapy for ESRD patients, but there is a severe disparity between the demand for kidneys for transplantation and the supply. This shortage is further complicated...

We consider the simultaneous design and operation of remnant inventory supply chains. Remnant inventory is generated when demand for various lengths of a product may be satisfied by existing inventory, or by cutting a large piece into smaller pieces. We formulate our problem as a two-stage...

This paper presents a detailed description of a particular class of deterministic single product Maritime Inventory Routing Problems (MIRPs), which we call deep-sea MIRPs with inventory tracking at every port. This class involves vessel travel times between ports that are significantly longer...