When testing the equality of the means from two independent normally distributed populations given that the variances of the two populations are unknown but assumed equal, the classical Student's two-sample t-test is recommended. If the underlying population distributions are normal with unequal...

There are many statistics which can be used to characterize data sets and provide valuable information regarding the data distribution, even for large samples. Traditional measures, such as skewness and kurtosis, mentioned in introductory statistics courses, are rarely applied. A variety of...

The randomized cluster design is typical in studies where the unit of randomization is a cluster of individuals rather than the individual. Evaluating various intervention strategies across medical care providers at either an institutional level or at a physician group practice level fits the...

When testing the equality of the means from two independent normally distributed populations given that the variances of the two populations are unknown but assumed equal, the classical two-sample t-test is recommended. If the underlying population distributions are normal with unequal and...

Background:Background: A recent clinical trial has demonstrated that patients with acute coronary syndromes (ACS) and the reduced function allele CYP2C19*2 (*2 allele), who are treated with thienopyridines, have an increased risk of adverse cardiac events with clopidogrel, but not with...

Background: Limited information exists on the best way to organise stroke rehabilitation after hospital discharge and the relative costs of such services. Objective: To review the evidence of the cost effectiveness of services that accelerate hospital discharge and provide home-based...