We consider the simultaneous design and operation of remnant inventory supply chains. Remnant inventory is generated when demand for various lengths of a product may be satisfied by existing inventory, or by cutting a large piece into smaller pieces. We formulate our problem as a two-stage...

The only therapy for a patient with end-stage liver disease (ESLD) is liver transplantation, which is performed by using either a cadaveric liver from a deceased donor or a portion of a living-donor's liver. This study addresses the following decision problem for an ESLD patient with an...

Cadaveric liver transplantation is the only viable therapy for end-stage liver disease patients without a living donor. However, this type of transplantation is hindered in the United States by donor scarcity and rapid viability decay. Given these difficulties, the current U.S. liver allocation...

Living donors are a significant and increasing source of livers for transplantation, mainly because of the insufficient supply of cadaveric organs. We consider the problem of optimally timing a living-donor liver transplant to maximize the patient's total reward, such as quality-adjusted life...

End-stage renal disease (ESRD) is the ninth-leading cause of death in the U.S. Transplantation is the most viable renal replacement therapy for ESRD patients, but there is a severe disparity between the demand for kidneys for transplantation and the supply. This shortage is further complicated...

This paper deals with the problems of checking strong solvability and feasibility of linear interval equations, checking weak solvability of linear interval equations and inequalities, and finding control solutions of linear interval equations. These problems are known to be NP-hard. We use some...

We consider a clique relaxation model based on the concept of relative vertex connectivity. It extends the classical definition of a k-vertex-connected subgraph by requiring that the minimum number of vertices whose removal results in a disconnected (or a trivial) graph is proportional to the...

Most optimization problems focus on efficiency-based objectives. Given the increasing awareness of system inequity resulting from solely pursuing efficiency, we conceptualize a number of new element-based equity-oriented measures in the dispersion context. We propose the equitable dispersion...