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Optimal decision-analytic designs are deterministic. Such designs are appropriately criticized in the context of clinical trials because they are subject to assignment bias. On the other hand, balanced randomized designs may assign an excessive number of patients to a treatment arm that is...
Persistent link: https://www.econbiz.de/10005447048
Consider designing a clinical trial in stages, with two treatments and N exchangeable patients to be treated. Responses are dichotomous. The problem is to decide how large each stage should be and how many patients should be assigned to each treatment during each stage. Information is updated...
Persistent link: https://www.econbiz.de/10005447078
The term "privately run economy," at the present stage [of development] in our country, refers to economic elements in which the assets of the enterprise belong to private individuals and are under a private ownership system, in which there is a set of labor relationships in which workers are...
Persistent link: https://www.econbiz.de/10008775324
A Bayesian adaptive design is proposed for a comparative two-armed clinical trial using decision-theoretic approaches. A loss function is specified, based on the cost for each patient and the costs of making incorrect decisions at the end of a trial. At each interim analysis, the decision to...
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This study examines the revaluation of shares surrounding the cancellation of mergers over the years 1976-85. The results are first categorized according to the party canceling the merger and then by subsequent merger activity. The results are as expected: target firms that become involved in...
Persistent link: https://www.econbiz.de/10005214252
The literature has suggested that earnings and earnings forecasts provide stronger signals than dividends about future performance of a firm. We test the information effects of simultaneous announcement of earnings and dividends in the Hong Kong market, distinguished by three interesting...
Persistent link: https://www.econbiz.de/10005701331
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