Human brain mapping, i.e. the detection of functional regions and their connections, has experienced enormous progress through the use of functional magnetic resonance imaging (fMRI). The massive spatio-temporal data sets generated by this imaging technique impose challenging problems for...

Extensions of the traditional Cox proportional hazard model, concerning the following features are often desirable in applications: Simultaneous nonparametric estimation of baseline hazard and usual fixed covariate effects, modelling and detection of time-varying covariate effects and nonlinear...

4208 In many practical situations, simple regression models suffer from the fact that the dependence of responses on covariates can not be sufficiently described by a purely parametric predictor. For example effects of continuous covariates may be nonlinear or complex interactions between...