In this paper we describe the special role of moment theory for the construction of optimal designs in statistical regression models. A careful introduction in the problem of designing experiments for certain polynomial regression models is given, and it is demonstrated that the maximization of...

In the common polynomial regression of degree m we determine the design which maximizes the minimum of the D-efficiency in the model of degree m and the D-efficiencies in the models of degree m – j,…, m + k (j, k 0 given). The resulting designs allow an efficient estimation of the...

In this note a matrix version of the q-d algorithm is introduced. It is shown that the algorithm may be used to obtain the coeÆcients of the recurrence relations for matrix orthogonal polynomials on the interval [0,∞) and [0;1] from its moment generating functional. The algorithm is...

For the compartmental model we determine optimal designs, which are robust against misspecifications of the unknown model parameters. We propose a maximin approach based on D-efficiencies and provide designs that are optimal with respect to the particular choice of various parameter regions.

A common approach in the design of experiment for the problem of comparing two means from a normal distribution is to assume knowledge of the ratio of the population variances. The optimal sampling ratio is proportional to the square root of this quantity. In this paper it is demonstrated that a...

In this article, the problem of constructing efficient discriminating designs in a Fourier regression model is considered. We propose designs which maximize the efficiency for the estimation of the coefficient corresponding to the highest frequency subject to the constraints that the...