In much of applied statistics variables of interest are measured with error. In particular, regression with covariates that are subject to measurement error requires adjustment to avoid biased estimates and invalid inference. We consider two aspects of this problem. Detection Limits (DL) arise...

In the first part of the dissertation, we derive two methods for responders analysis in longitudinal data with random missing data. Often a binary variable is generated by dichotomizing an underlying continuous variable measured at a specific point in time according to a prespecified threshold...

Bulgaria's transition to a market economy has coincided with a large increase in wage inequality. Given the emphasis on wage leveling in pre-transition Bulgaria, the rise in wage inequality may be due to managers rewarding more productive workers; or it may be the result of rewarding...

The aim of this paper is to elicit the sensitivity of farmers to payments for agro-environmental services in acontext of strong agro-ecological and policy constraints. We present results from a choice experimentsurvey performed among the whole population of agricultural decision-makers (104) in...

This dissertation focuses on two topics in semiparametric statistical methods and their applications in medical science: (1) prediction of patients? lifetimes based on their risk profiles; (2) estimation of dynamic exposure effects on survival outcomes. In Chapter II, we develop multiple...

In many clinical studies, researchers are mainly interested in studying the effects of some prognostic factors on the hazard of failure from a specific cause while individuals may failure from multiple causes. This leads to a competing risks problem. Often, due to various reasons such as finite...

An important challenge in statistical modeling involves determining an appropriate structural form for a model to be used in making inferences and predictions. Missing data is a very common occurrence in most research settings and can easily complicate the model selection problem. Many useful...

We consider estimation in generalized linear mixed models (GLMM) for longitudinal data with informative dropouts. At the time a unit drops out, time-varying covariates are often unobserved in addition to the missing outcome. However, existing informative dropout models typically require...

When data are missing at random, the missing-data mechanism can be ignored but this assumption is not always intuitive for general patterns of missing data. In part I, we consider maximum likelihood (ML) estimation for a non-ignorable mechanism which is called almost missing at random (AMAR). We...

Multiple outcomes are often used to properly characterize an effect of interest. This paper proposes a latent variable model for the situation where repeated measures over time are obtained on each outcome. These outcomes are assumed to measure an underlying quantity of main interest from...