Renard, Didier; Geys, Helena; Molenberghs, Geert; … - In: Journal of Applied Statistics 30 (2003) 2, pp. 235-247
The objective of this paper is to extend the surrogate endpoint validation methodology proposed by Buyse et al. (2000) to the case of a longitudinally measured surrogate marker when the endpoint of interest is time to some key clinical event. A joint model for longitudinal and event time data is...