Heitjan, Daniel F.; Moskowitz, Alan J.; Whang, William - In: Health Economics 8 (1999) 3, pp. 191-201
Estimation of the incremental cost-effectiveness ratio (ICER) is difficult for several reasons: treatments that decrease both cost and effectiveness and treatments that increase both cost and effectiveness can yield identical values of the ICER; the ICER is a discontinuous function of the mean...