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The concept of genetic identity–by–descent (IBD) has markedly advanced our understanding of the genetic similarity among relatives and triggered a number of developments in epidemiological genetics. However, no empirical measure of this relatedness throughout the whole human genome has yet...
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The moment magnitude (M <Subscript>w</Subscript>) 9.0 Tohoku-Oki Earthquake occurred on March 11, 2011, generating an unusually large tsunami. The seismic shocks and tsunami inundation severely damaged the Fukushima Daiichi Nuclear Power Plant. Radionuclide emission due to reactor breakdown contaminated wide areas of...</subscript>
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The Genome-Wide Association Study (GWAS) is the predominant tool to search for genetic risk variants that contribute to complex human disease. Despite the large number of GWAS findings, variants implicated by GWAS are themselves unlikely to fully explain the heritability of many diseases. In...
Persistent link: https://www.econbiz.de/10009482947
The relationship between speciation times and the corresponding times of gene divergence is of interest in phylogenetic inference as a means of understanding the past evolutionary dynamics of populations and of estimating the timing of speciation events. It has long been recognized that gene...
Persistent link: https://www.econbiz.de/10005459155
A compilation of paper presented in the workshop entitled Biodiversity and Sustainable Use of Fish in the Coastal Zone. The workshop was convened in May 1999 at WRI, to give the project team, invited expert and participants from Ghana and other sub-Saharan Africa countries an opportunity to...
Persistent link: https://www.econbiz.de/10005464196
In this paper a widely-studied model in Population Genetics, the so-called Infinitely- Many-Alleles model with neutral mutation, is reinterpreted in terms of a timedependent Bayesian nonparametric statistical model, where the prior of the model is described by the Neutral Fleming-Viot process. A...
Persistent link: https://www.econbiz.de/10004972517
This paper provides a construction of a Fleming-Viot measure valued diffusion process, for which the transition function is known, by extending recent ideas of Gibbs sampler based Markov processes. In particular, we concentrate on the Chapman-Kolmogorov consistency conditions which allows a...
Persistent link: https://www.econbiz.de/10004980483