The application of stochastic heuristic, like tabu search or simulated annealing, to address hard discrete optimization problems has been an important advance for efficiently obtaining good solutions in a reasonable amount of computing time. A challenge when applying such heuristics is assessing...

Combination vaccines have become the preferred choice for immunizing children in high- and middle-income countries. However, these new vaccines are prohibitively expensive for low-income countries, causing them to rely on older, less-expensive vaccines. This product divergence decreases...

An increasing number of legislative efforts have been undertaken to prohibit the use of hand-held wireless devices while driving. As of July 2012, ten states and the District of Columbia enforce laws banning the use of hand-held cell phones while driving. Thirty-nine states and the District of...

Bracketology, the art of successfully picking all the winners in the National Collegiate Athletic Association's (NCAA) annual men's Division I college basketball championship tournament, has become a favorite national activity. In spite of the challenges and uncertainty faced in this endeavor,...

Vaccination against infectious disease is an extremely important public health endeavor. Yet, in the past 40 years, the manufacture of pediatric vaccines has become less profitable due to rising costs and limited demand, inducing many pharmaceutical companies to leave the market. To ensure the...

A number of methods have been proposed for predicting game winners in the National Collegiate Athletic Association's (NCAA) annual men's college basketball championship tournament. Since 1985, more than 70% of the teams in the fourth, fifth, and sixth rounds of the tournament have been...

Vehicle travel and obesity rates in the United States have surged in recent decades. This paper contributes to the mounting evidence of a link between them by drawing attention to a very close relationship between trends in miles driven per licensed driver and adult obesity rates six years...