In many applications, researchers are interested in estimating the mean of a multivariate normal random vector whose components are subject to order restrictions. Various authors have demonstrated that the likelihood-based methodology may perform poorly under certain conditions for such...

The paper presents a case-study of skin fibromas among male rats in the 2-year cancer bioassay of methyleugenol that was conducted by the US National Toxicology Program (NTP). In animal carcinogenicity experiments such as this one, tumour rates are often compared with the Cochran-Armitage (CA)...

We consider Bayesian inference about collections of unknown distributions subject to a partial stochastic ordering. To address problems in testing of equalities between groups and estimation of group-specific distributions, we propose classes of restricted dependent Dirichlet process priors....

We propose 'Dunnett-type' test procedures to test for simple tree order restrictions on the means of "p" independent normal populations. The new tests are based on the estimation procedures that were introduced by Hwang and Peddada and later by Dunbar, Conaway and Peddada. The procedures...

In this article we develop a new test procedure for testing a linear hypothesis in a fixed effects linear model with heteroscedastic errors. This test is based on the ordinary least squares estimator (OLSE) of the regression parameter and uses the variance estimator of OLSE that accounts for...

For multivariate nonlinear regression and multivariate generalized linear regression models, with repeated measurements and possible missing values, we derive the asymptotic normality of a general estimating equations estimator of the regression matrix. We also provide consistent estimators of...